Goat Secondary Antibodies
Cayman Chemical 4-MethylumbelIferon 50g
A synthetic coumarin with diverse biological activities; inhibits hyaluronic acid synthesis in PC3-ML and DU145 cells (IC50s = ~0.4 mM for both); inhibits the growth of PC3-ML, DU145, C4-2B, LNCaP, and LAPC-4 prostate cancer cells (IC50s = 0.2-0.4 mM) and invasion and chemotactic motility of PC3-ML and DU145 cells in vitro; reduces tumor growth and microvessel density in a PC3-ML mouse xenograft model at 225 and 450 mg/kg twice per day; active against H. pylori and V. cholerae in vitro (MICs = 59 and 100-200 μg/ml, respectively); ex/em = 320 and 360 nm at low and high pH, respectively/455 and 445 nm at low and high pH, respectively.
Cayman Chemical AmIlorIdehydrochlorIdehy 5g
A potassium-sparing diuretic; an ENaC inhibitor (K0.5 = 2.6 µM); inhibits sodium transport from bovine kidney cortex membrane vesicles (IC50 = 0.4 µM); inhibits u-PA (Ki = 7 µM) and the cardiac Na+/H+-ATPase (IC50 = 83.8 µM); inhibits calcium currents mediated by TRPP3 (IC50 = 143 µM); reduces mean arterial pressure in spontaneously hypertensive rats at 30 mg/kg
